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Search Results for " myeloid-derived growth factor "

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T71400 Quizartinib HCl

Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro...
T2066 Quizartinib

AC220,奎扎替尼

Apoptosis; FLT; Autophagy; Ligands for Target Protein for PROTAC Angiogenesis; Apoptosis; Autophagy; PROTAC; Tyrosine Kinase/Adaptors
Quizartinib (AC220) 是一种具有口服活性的高选择性Ⅱ 型 FLT3酪氨酸激酶抑制剂,可诱导细胞凋亡。它抑制 Wt FLT3 和 突变型 FLT3-ITD 自磷酸化,IC50分别为 4.1 nM 和 1.1 nM。它可通过优化的 linker 与 VHL 配体连接,从而形成 PROTAC Flt3 降解剂。

化合物

Quizartinib HCl
Cat.No: T71400
Synonym:
Target:
Quizartinib
Cat.No: T2066
Synonym: AC220,奎扎替尼
Target: Apoptosis, FLT, Autophagy, Ligands for Target Protein for PROTAC
Cat. No. Product Name Species Expression System
TMPY-00034 SF20 Protein, Human, Recombinant (His)

myeloid-derived growth factor...

Human HEK293 Cells
SF20 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q969H8.
TMPY-04264 SF20 Protein, Human, Recombinant (mFc)

IL27,EUROIMAGE1875335,myeloid-derived ...

Human HEK293 Cells
SF20 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q969H8.

重组蛋白

SF20 Protein, Human, Recombinant (His)
Cat.No: TMPY-00034
Species: Human
Expression System: HEK293 Cells
SF20 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04264
Species: Human
Expression System: HEK293 Cells
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